In recent years, public health practitioners have aimed to improve the food environment and purchasing patterns in small food stores, yet studies summarizing these interventions and their effectiveness are lacking. This paper reviews small-store interventions and discusses their impact on healthy food access and consumption. Findings of the review indicate that small-store interventions significantly improve the availability of healthy foods, the purchase and consumption of those foods, and consumer knowledge. Multi-pronged strategies combining environmental and behavioral approaches in small-store interventions were most effective.