Food retail is a key setting that influences the diets and health of children and families. The healthfulness of foods and beverages found in retail food stores differs widely across the United States, both by location of the store (e.g., rural vs. urban or low vs. high-income neighborhoods) as well as by store type (e.g., supercenters/big box stores, grocery stores, corner stores, online food shopping, etc.). Research in this area focuses on investigating strategies to improve the availability, accessibility, affordability, and demand for healthier products within the food retail setting.