In-store food marketing can influence food purchasing behaviors, but much remains to be learned about what food marketing practices in grocery stores can help address the growing burden of obesity. This paper synthesizes research and publications from industry and academic sources on the topic and provides direction for developing and evaluating promising interventions. Findings from the review suggest several in-store marketing strategies to promote healthful eating by increasing availability, affordability, prominence, and promotion of healthful foods and/or restricting or de-marketing unhealthy foods.